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New untiulcerous and anti-inflammatory drug ALTAN

              Polyphenol substances contained in fruit systems of Alnus glutinosa L. Gaertn. have expressed anti-inflammatory, styptic, hemostatic and disinfecting properties. On the basis of dry extract of fruit systems of Alnus glutinosa L. Gaertn a series of medicinal preparations was developed. Antiulcerous preparation Altan in the form of coated tablets 0.01 g is intended for complex therapy of chronic gastritis, gastroduodenitis and gastroduodenal ulcer. This preparation is low-toxic (VD50 8500 mg/kg, rats), has no cumulative properties, does not act on secretory function of the stomach. Altan tablets must be ingested 1 hr before meals 2 or 3 times a day. Depending on disease gravity the therapy course may be 1 to 2 months. During comparative study of antioxidant properties of ellagotannins and bioflavonoids advantages of Altan as a promising preparation have been shown. 2% Altan ointment is a preparation having expressed wound-healing, reparative and antimicrobial effects, which is intended for healing post-injure, purulent wounds and burns. The indicated pharmacological properties of Altan ointment affect injure process progress and on healing time and quality. On the basis of vegetative substances of Altan technologies of production of tablets with stomach-soluble coat and of suppositories containing dry matricary extract were also developed.

Published: 12.09.2000