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Cefopectam Cefoperazone, combinations/J01D D62
Cefopectam

Cefoperazone, combinations/J01D D62

Active ingredients:

cefoperazone (as cefoperazone sodium sterile) -  500 mg or 1 g, and sulbactam (as sulbactam sodium sterile) - 500 mg or 1 g, respectively.

Cefopectam is a combination of sulbactam sodium and cefoperazone sodium. Sulbactam sodium is an irreversible inhibitor of the most important beta-lactamases produced by beta-lactam antibiotic-resistant organisms. Cefoperazone sodium is a third-generation, semi-synthetic cephalosporin antibiotic. Sulbactam prevents the destruction of cephalosporins by resistant organisms. Cefopectam is active against all organisms susceptible to cefoperazone, in particular, gram-positive and gram-negative bacteria such as Pseudomonas aeruginosa and anaerobes. In addition, a synergistic effect is observed that is up to 4-fold reduction in minimum inhibitory concentrations for the combination as compared with  the effects of each single component.

Indications

The treatment of infectious inflammatory diseases caused by susceptible organisms:

  • upper and lower respiratory tract infections;
  • upper and lower urinary tract infections;
  • peritonitis, cholecystitis, cholagitis and other intra abdominal infections;
  • septicaemia;
  • meningitis;
  • skin and soft tissue infections;
  • infections of bones and joints;
  • pelvic inflammatory diseases, endometritis, gonorrhoea and other genital infections.

Dosage and pharmaceutical form:

powder for solution for injection, 500 mg/500mg or 1g/1g in vial; 1 vial per carton; 5 vials in cassette, 1 cassette per carton.