Active ingredients:

ceftriaxone (as ceftriaxone sodium sterile) -  500 mg or 1000 mg, and sulbactam (as sulbactam sodium sterile) - 250 mg or 500 mg, respectively.

Ceftractam is a combination of ceftriaxone sodium and sulbactam sodium. Ceftriaxone sodium is a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic, has bactericidal activity resulting from the inhibition of transpeptidase enzymes, and bacterial cell wall peptidoglycan synthesis. Sulbactam sodium is an irreversible inhibitor of the most important beta-lactamases produced by beta-lactam antibiotic-resistant organisms. The sulbactam/ceftriaxone combination is active against all organisms susceptible to ceftriaxone, in particular, gram-positive and gram-negative bacteria and anaerobes. In addition, the medication is active against microorganisms resistant to penicillins, early generation cephalosporins, and aminoglycosides.

Indications

The treatment of infectious inflammatory diseases caused by susceptible organisms:

• lower respiratory tract infections;
• acute bacterial otitis media;
• skin and soft tissue infections;
• kidney and urinary tract infections;
• infections of bones and joints;
• septicaemia;
• intra abdominal infections (including peritonitis, biliary and digestive tract infections);
• bacterial meningitis;
• gonorrhoea;
• perioperative prophylaxis.

Dosage and pharmaceutical form:

powder for solution for injection 500 mg/250 mg or 1000 mg/500 mg per vial; 1 vial; 1 vial per carton; 5 vials in cassette, 1 cassette per carton.