Active ingredients:

Allopurinol - 100 mg.

ALLOPURINOL is is a xanthine-oxidase inhibitor and is used for the treatment of gout. ALLOPURINOL and its main metabolite oxipurinol lower the level of uric acid in plasma and urine by inhibition of xanthine oxidase, the enzyme catalyzing the oxidation of hypoxanthine to xanthine and xanthine to uric acid. This reduces serum urates and prevents their accumulation in the tissues and kidneys.

Indications

ADULTS:

ALLOPURINOL is indicated tor the treatment of:

• hyperuricemy (the serum level of uric acid is 500 mkmol (8.5 mg/100 ml) or higher and non-diet controlled);
• diseases caused by increased serum uric acid levels, especially in patients with gout, urate nephropathy and urate urolithiasis;
• secondary hyperuricemy;
• primary and secondary hyperuricemy, accompanied by various hemoblastoses (acute leucosis, chronic myeloleukemia, lymphosarcoma);
• cytostatic therapy of tumors; myeloproliferative disorders.

CHILDREN:

• urate nephropathy due to the treatment of leukemia;
• secondary hyperuricemy;
• congenital deficiencies such as Lesch-Nyhan syndrome (partial or complete deficiency of hypoxanthine-guanine phosphoribosyltransferase) and congenital deficiency of adenine-phosphoribosyltransferase.

Dosage and pharmaceutical form:

tablets 100 mg, 10 tablets in blister, 5 blisters in package.